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Lecture Hall ICM - Internationales Congress Center München European Conferences on Biomedical Optics (ECBO) > Preclinical and Clinical Optical Diagnostics > Clinical Applications: Spectroscopy
09:15-09:30 h | ICM - Internationales Congress Center München ICM Room 2
Subjects: Biophotonics and Medical Engineering
Chairman: J. Quincy Brown (, Tulane Univ.)
Wound healing is a biological response in order to recover the tissue stability after injury. The impaired healing by third-degree, when the damage achieves the major part of dermis, is defined in four sequential and overlapping phases: Inflammation, transition, proliferative and maturative. The role of biochemical cascade associated in each phase are still not fully understood, thus systematic evaluations tests are crucial. In fact, the gold standard to interrogate the molecular signature of wound healing is concern on immunohistochemical analysis. This approach tends to be laborious, time-consuming and require multiple assays. Since Fourier transform infrared spectroscopy (FTIR) has been demonstrated in other studies to provide molecular change report upon biological samples, the present study aims to estimate the feasibility of FTIR to discriminate healthy and burned skin throughout wound stages.