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Imaging of LED-excited autofluorescence photobleaching rates for skin diagnostics

JUN
24
2019
24. JUN 2019

Poster Hall B0 European Conferences on Biomedical Optics (ECBO) > Preclinical and Clinical Optical Diagnostics > Lunch Break and Poster Session - Monday

12:45-14:15 h | Hall B0 Hall B0, ICM

Subjects: Biophotonics and Medical Engineering

Type: Poster

Speech: English

The aim of this study is to develop a novel non-invasive approach for skin cancer (melanoma, basal cell and squamous cell carcinomas) diagnostics by mapping the AF intensity decrease (photo-bleaching) rates under continuous 405 nm LED excitation. For parametric mapping of skin AF intensity decrease rates a sequence of filtered AF imaging under 405 nm LED excitation for 20 seconds at a power density of ~7 mW/cm2 with a frame rate 0.5 fps was recorded and analyzed by cloud-based prototype device. Several clinical cases and potential future applications of the proposed autofluorescence photobleaching rate imaging technique are discussed. This work has been supported by two European Regional Development Fund projects “Time-resolved autofluorescence methodology for non-invasive skin cancer diagnostics” (No. 1.1.1.2/16/I/001, agreement No. 1.1.1.2/VIAA/1/16/014) and “Portable device for noncontact skin cancer early diagnostics” (No. 1.1.1.1/16/A/197).

Informations

Author,
Univ. of Latvia

Alexey Lihachev
Alexey Lihachev

Location

Eingang
Nord-West
ICM
Eingang
Nord
Eingang
West
Atrium
Eingang
Nord-Ost
Eingang
Ost
Conference
Center Nord
Freigelände
C1
C2
C3
C4
C5
C6
B0
B1
B2
B3
B4
B5
B6
A1
A2
A3
A4
A5
A6

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