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Poster Hall B0 European Conferences on Biomedical Optics (ECBO) > Preclinical and Clinical Optical Diagnostics > Lunch Break and Poster Session - Monday
12:45-14:15 h | Hall B0 Hall B0, ICM
Subjects: Biophotonics and Medical Engineering
In present time, terahertz (THz) technologies are being actively investigated in many areas, including various biophotonic applications such as cancer diagnosis. In particular, the intraoperative cancer diagnosis using THz spectroscopy is a promising area of medical research. This is due to the THz radiation is low energy, non ionizing and harmless to biological tissues. The THz frequency range is remarkable in problems of biomedical diagnostics because it has characteristic absorption peaks of various biological objects in particular various biomolecules. Also THz radiation is strongly absorbed by intermolecular bindings, for example hydrogen compounds present in water, and NH-bonds present in proteins. Oncological tissues contain more water than healthy ones as well as a different morphological structure. Based on this fact healthy and tumor tissues can be effectively distinguished, as well as the boundary between them. In this work, we investigated fresh samples of healthy and cancer tissues of human stomach using terahertz time domain spectroscopy in reflection mode. A difference in their optical properties and spectral characteristics in the frequency range of 0.1 – 0.6 THz was obtained. All oncological samples are characterized by higher refraction and absorption compared with healthy ones. This study confirms the effectiveness of using THz reflectometry for the intraoperative diagnostics of boundaries of tumor and healthy tissues, and can be used as the basis for further development and practical implementation in this area.