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Terahertz time-domain spectroscopy for human gastric cancer diagnosis

JUN
24
2019
24. JUN 2019

Poster Hall B0 European Conferences on Biomedical Optics (ECBO) > Preclinical and Clinical Optical Diagnostics > Lunch Break and Poster Session - Monday

12:45-14:15 h | Hall B0 Hall B0, ICM

Subjects: Biophotonics and Medical Engineering

Type: Poster

Speech: English

In present time, terahertz (THz) technologies are being actively investigated in many areas, including various biophotonic applications such as cancer diagnosis. In particular, the intraoperative cancer diagnosis using THz spectroscopy is a promising area of medical research. This is due to the THz radiation is low energy, non ionizing and harmless to biological tissues. The THz frequency range is remarkable in problems of biomedical diagnostics because it has characteristic absorption peaks of various biological objects in particular various biomolecules. Also THz radiation is strongly absorbed by intermolecular bindings, for example hydrogen compounds present in water, and NH-bonds present in proteins. Oncological tissues contain more water than healthy ones as well as a different morphological structure. Based on this fact healthy and tumor tissues can be effectively distinguished, as well as the boundary between them. In this work, we investigated fresh samples of healthy and cancer tissues of human stomach using terahertz time domain spectroscopy in reflection mode. A difference in their optical properties and spectral characteristics in the frequency range of 0.1 – 0.6 THz was obtained. All oncological samples are characterized by higher refraction and absorption compared with healthy ones. This study confirms the effectiveness of using THz reflectometry for the intraoperative diagnostics of boundaries of tumor and healthy tissues, and can be used as the basis for further development and practical implementation in this area.

Informations

Author,
ITMO Univ.

Roman Grigorev
Roman Grigorev

Location

Eingang
Nord-West
ICM
Eingang
Nord
Eingang
West
Atrium
Eingang
Nord-Ost
Eingang
Ost
Conference
Center Nord
Freigelände
C1
C2
C3
C4
C5
C6
B0
B1
B2
B3
B4
B5
B6
A1
A2
A3
A4
A5
A6

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