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Determination of optical properties of human tissues obtained from parotidectomy in the spectral range of 250 to 800 nm

JUN
24
2019
24. JUN 2019

Lecture Hall A1 European Conferences on Biomedical Optics (ECBO) > Preclinical and Clinical Optical Diagnostics > Tissue Characterization and Analysis

14:15-14:30 h | Hall A1 Room 6 "Charles Townes"

Subjects: Biophotonics and Medical Engineering

Chairman: J. Quincy Brown (, Tulane Univ.)

Type: Lecture

Speech: English

The absorption coefficient µ_a and scattering coefficient µ_s of different tissue types obtained during parotidectomy are determined in the wavelength range of 250 nm to 800 nm. These values are obtained by high precision integrating sphere measurements in combination with an optimized inverse Monte Carlo simulation (iMCS). To conserve the optical behavior of living tissues, the optical spectroscopy measurements are performed directly after tissue removal. This study includes fresh samples of the ear, nose and throat (ENT) region, as muscle tissue, nervous tissue, white adipose tissue, stromal tissue and parotid gland of five patients. The measured behavior of adipose corresponds well to the literature, which sustains the applied method. It is shown, that muscle is well supplied with blood as it features the same characteristic peaks at 430 nm and 555 nm in the absorption curve. The parameter µ_s decreases for all tissues type above 570 nm. The accuracy is adequate for the purposes of providing µ_a and µ_s of different human tissue types as muscle, fat or gland tissue, which are embedded in large complex structures such as in the ENT area. It is therefore possible for the first time to present reasonable results for the optical behavior of human soft tissue located in the ENT area and in the near-UV, visual and near-IR areas.

Informations

Location

Eingang
Nord-West
ICM
Eingang
Nord
Eingang
West
Atrium
Eingang
Nord-Ost
Eingang
Ost
Conference
Center Nord
Freigelände
C1
C2
C3
C4
C5
C6
B0
B1
B2
B3
B4
B5
B6
A1
A2
A3
A4
A5
A6

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