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Lecture Hall ICM - Internationales Congress Center München European Conferences on Biomedical Optics (ECBO) > Translation of Lasers and Biophotonics Technologies and Procedures: Toward the Clinic > Optical Diagnostic Techniques
17:30-17:45 h | ICM - Internationales Congress Center München ICM Room 11
Subjects: Biophotonics and Medical Engineering
Chairman: Marie Louise Groot (, Vrije Univ. Amsterdam)
Third and second harmonic generation (THG/SHG) microscopy is a novel imaging technique that has been suggested as a promising clinical tool, mainly for cancer diagnosis. Here, we test for the first time a compact, transportable ex-vivo THG/SHG microscope (Tritos Diagnostics B.V.) for clinical use. In lung surgery, immediate feedback on the nature of the excised tissue is important. We will present the first results of an ongoing study in which we image both lung tumor tissue immediately after excision and frozen section biopsies, and compare the images to the golden standard histology. Prior to this study, we performed a set of experiments collecting 3D images of mouse lung tissue to show that the combination of THG and SHG microscopy reveals key lung morphology components.